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Italy Cruises

The richest historic and cultural heritage in the world, view all italy ports.

  • Ancona (Urbino), Italy
  • Bari, Italy
  • Brindisi (Lecce) , Italy
  • Cagliari (Sardinia) , Italy
  • Civitavecchia (Rome) , Italy
  • Genoa (Portofino) , Italy
  • La Spezia (Cinque Terre) , Italy
  • Livorno (Florence) , Italy
  • Messina (Taormina) , Italy
  • Naples (Pompeii) , Italy
  • Palermo (Monreale) , Italy
  • Ravenna, Italy
  • Syracuse, Italy
  • Trieste (Venice), Italy
  • Venice - Marghera, Italy

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Mediterranean

The historic ports of Italy - from Bari to Venice, Genoa to Naples   Fascinating archaeological sites and delicious food with unexpected flavours   Enjoy the Greek and Andalusian sun and the refined French towns

Mediterranean Cruises

This cruise offers the opportunity to visit and learn about countries and peoples facing this sea and their millenary history just like ancient mariners did as they sailed from Italy to the Greek Islands . 

Travelling on an MSC Cruise will give you the opportunity to get a closer look at the historic ports of Italy, from Rome to Venice , from Genoa to Naples , to appreciate the picturesque and refined French towns of Cannes , to immerse yourself into Spanish culture in Barcelona , Malaga , Valencia and Ibiza . Take advantage of the excursions organized by our staff to enjoy the Greek sunshine while visiting important archaeological sites or develop a passion for Croatian music. If the Mediterranean is not enough, you can choose MSC cruises that head beyond Gibraltar for a quick visit to the Portuguese coasts of Lisbon and Funchal and the Canary Islands. Italy , Spain and Morocco , the East and the West have never been so close as on a cruise on MSC Cruises.

Ports in the Mediterranean

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msc tour mediterraneo

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MSC Cruises Mediterranean Cruises

MSC Cruises: Kids Sail FREE on select sailings*

MSC Cruises: Kids Sail FREE on select sailings*

MSC Cruises Military Discount: up to 10% OFF*

MSC Cruises Military Discount: up to 10% OFF*

MSC Cruises Mediterranean cruises from $125*

MSC Cruises Mediterranean cruises from $125*

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When it comes to MSC Cruises, Mediterranean cruises are their specialty. With European-style service, extensive knowledge of the area and attractions within, and regional touches that will bring a smile to your face, these vacation options are a true delight. Explore a region featuring castles, palaces, and quaint towns. Go on a culinary adventure in search of the finest fare—feasting upon seafood in Italy or puffy pastries in France. Enrich yourself with a salsa dancing lesson from a real ‘bailador’ or bask in the architectural excellence of Rome. Sail with the best on a MSC Cruises Mediterranean cruise.

View MSC Cruises to Mediterranean

Things to Do on a Mediterranean Cruise with MSC Cruises

The Mediterranean is one of the most creative and inspiring regions in the world. On an MSC Cruises sailing to the Mediterranean you can visit pyramids in Egypt, taste wine in Barcelona and learn about Greek gods in Athens.

MSC Cruises coast line of Dubrovnik

  • Dubrovnik and Its Old City Walls (Dubrovnik, Croatia) A UNESCO World Heritage Site, the “Pearl of the Adriatic” is the amazing historical center of Dubrovnik that is surrounded by magnificent city towers and architecture. Visit this and the old city walls that were built in the 12th century to keep invaders out and are now a tourist attraction because of the beauty of the preserved construction.  

MSC Cruises african oasis in the desert in Sakkara

  • They Pyramids and Sakkara Desert Safari (Alexandria, Egypt) For a truly unique exploration, visit the famous Pyramids of Egypt (Khufu, Khafra and Menkaure) and the famous Sphinx. Ride on the back of a camel to the Sakkara Country Club where you’ll visit the Pyramid of Sakkara and learn how to make paper from reeds at the Papyrus Institute.  

MSC Cruises architecture of La Sagrada-Barcelona

  • Highlights of Barcelona, Montserrat and Wine Tasting (Barcelona, Spain) Barcelona is full of extravagant art and architecture, and in this MSC Cruises tour you’ll have a chance to see Paseo de Gracia and Sagrada Familia, both designed by Gaudi. You’ll also visit Montserrat, where the Virgin of Montserrat statue stands. Before you end this excursion, you’ll also visit the Cavas Vilarnau cellars for a tasting of sparkling wine and Spanish champagne.  

MSC Cruises architectural detail of Hasan Mosque II

  • City Tour and Hassan II’s Mosque (Casablanca, Morocco) Casablanca rose after a 1755 earthquake rocked the old city of Anfa, leading many citizens to abandon the old city for Casablanca. Be sure to visit the beautiful architecture of the Cathedral of Notre Dame de Lourdes and one of the largest mosques in the Islamic world, the Mosque of Hassan II.  

MSC Cruises coast of Capri

  • Capri Island Tour (Naples, Italy) One of the most relaxing and beautiful island tours awaits you as you travel through the Bay of Naples and into the Island of Capri. You’ll dock at the Marina Grande and reach the Capri city center for an opportunity to explore the charismatic streets through the square of Piazza Umberto.  

MSC Cruises historic landmark Parthenon

  • Athens and Acropolis (Piraeus-Athens, Greece) Visit the city that is known for developing the foundation of western civilization and modern democracy, the stunning Athens, Greece. You’ll get great photograph opportunities at Athens’ most popular and historic landmarks, Acropolis and the Parthenon.  

Top 10 MSC Cruises Mediterranean Cruises

  • MSC World Europa 7 NIGHT Mediterranean - Western CRUISE Departing From Barcelona, Spain (Nov 2024 - Oct 2026)
  • MSC Sinfonia 3 NIGHT Mediterranean - Eastern CRUISE Departing From Bari, Italy (Nov 2024)
  • MSC Sinfonia 4 NIGHT Mediterranean - Eastern CRUISE Departing From Bari, Italy (Nov 2024)
  • MSC Sinfonia 7 NIGHT Mediterranean - Eastern CRUISE Departing From Bari, Italy (Nov 2024 - May 2026)
  • MSC Fantasia 7 NIGHT Mediterranean - Western CRUISE Departing From Barcelona, Spain (Nov 2024 - Mar 2026)
  • MSC World Europa 7 NIGHT Mediterranean - Western CRUISE Departing From Marseille, France (Nov 2024 - Oct 2026)
  • MSC Lirica 10 NIGHT Mediterranean CRUISE Departing From Venice, Italy (Nov 2024)
  • MSC Lirica 11 NIGHT Mediterranean CRUISE Departing From Venice, Italy (Nov 2024)
  • MSC Lirica 12 NIGHT Mediterranean CRUISE Departing From Venice, Italy (Nov 2024)
  • MSC Lirica 4 NIGHT Mediterranean CRUISE Departing From Venice, Italy (Nov 2024)

MSC Cruises Mediterranean Departure Ports

Learn more about each of the possible departure ports for a Mediterranean cruise with MSC Cruises. Your MSC Cruises Mediterranean cruise could leave from any of the following cities:

Alicante, Spain

Alicante, Spain

Escape to this Mediterranean city of Alicante, Spain with enticing sandy beaches and museums.

Ancona, Italy

Ancona, Italy

A beautiful spot along the Adriatic Sea, Ancona offers cruisers an interesting take on Italian history, especially given its history as a Papal State.

Barcelona, Spain

Discover imaginative architecture, impressive Spanish dishes and beautiful excursions into nature when you cruise to Barcelona, the capital of Catalonia.

Bari, Italy

Bari, Italy

Cruise to Bari and explore this extraordinary city in the South of Italy. Highlights include its interesting history and friendly people, who are always ready to show you their way of life.

Brindisi, Italy

Brindisi, Italy

This ancient city is sure to charm with its immaculate architecture, tranquil harbor and coastline, delicious cuisine as well as its Greek-Italian feel.  

Cagliari, Sardinia, Italy

Cagliari, Sardinia, Italy

As the second largest island in the Mediterranean, this island offers wonderful blue lagoons, ancient buildings, white sand beaches and rich culture.  

Cannes, France

Cannes, France

Live the glamorous life in Cannes, the city in the South of France known as the host of the yearly Cannes Film Festival.

Civitavecchia (Rome), Italy

A cruise to Civitavecchia is a chance for you to hop a quick train to Rome and explore the enormous history through ruins, galleries and The Vatican museums.

Genoa, Italy

Genoa, Italy

Cruise to the historical port city of Genoa for a laid back walk through history in the city’s well-preserved streets, and be sure to try the local foods like pesto and focaccia bread.

Istanbul, Turkey

Istanbul, Turkey

Istanbul is a unique city that blends its two distinct influences – from its founding as the Christian capital of Constantinople to the Ottoman ruled Istanbul. Today you can discover both eras and the modern beauty in this thriving city.

Izmir, Turkey

Izmir, Turkey

Ismir is a bustling metropolitan center located in Western Turkey, surrounded by the waters of the Gulf of Izmir and the Gediz River.

Kusadasi (Ephesus), Turkey

Kusadasi (Ephesus), Turkey

Kusadasi welcomes visitors from all over to discover the ruins of the ancient city of Ephesus, a powerful city that was once home to the Virgin Mary.

La Spezia (Cinque Terre), Italy

La Spezia (Cinque Terre), Italy

Start your own artistic renaissance on a cruise to La Spezia, part of the beautiful coastal landscape of Northern Italy near Tuscany, Florence, Pisa and Livorno.

Lisbon, Portugal

Lisbon, Portugal

Lisbon has deep cultural roots that are exposed through ruins and museum artifacts. Cruise to Lisbon and discover the culture and history of Portugal in its capital city.

Livorno (Florence/Pisa), Italy

Livorno (Florence/Pisa), Italy

As a port city on the western coast of a country known for its magnificent art, the cruise port of Livorno, Italy is a great starting point to exploring the phenomenal paintings and sculptures found in Italy.

Malaga, Spain

Malaga, Spain

Cruise to Malaga, the celebrated home of Picasso, one of the modern era’s most influential artists. Other attractions include the beautiful Moorish castles and mesmerizing coastal cliffs.

Marseille, France

Marseille, France

Marseilles, France’s second most popular city, offers cruisers a vast landscape to discover the area’s ancient history and relish the more modern lifestyle of the French living off the coast of the Mediterranean.

Messina, Sicily, Italy

Messina, Sicily, Italy

Enjoy Messina, the gateway to Sicily, the largest island in the Mediterranean with a proud heritage and world renowned food.

Miami, Florida

In Miami, you’ll enjoy a small taste of the tropical weather many of you will experience during your cruise, and you’ll see why Miami is one of the most popular places to live in America.

Naples, Italy

Naples, Italy

Prepare your appetite if you plan to visit Naples, for it is home to many of Italy’s most famous culinary traditions. Naples is more than just great food, so make time to visit the beautiful cathedrals and enriching museums.

Olbia, Italy

Olbia, Italy

Sail into Olbia, Italy to experience a sunny taste of Italy's Emerald Coast with beautiful beaches, scenic islands and secluded coastal trails.

Palermo, Sicily, Italy

Palermo, Sicily, Italy

Explore the varied history and culture of Palermo, Sicily’s capital city, and enjoy its diverse history, culture and art.

Palma De Mallorca, Spain

Palma De Mallorca, Spain

The island of Mallorca can boast of an impressive port city where the old and new worlds dwell in perfect harmony.

Piraeus (Athens), Greece

Learn about the Greek gods and the early philosophy of Socrates when you visit the incredible ruins left in Athens, Greece. At night, go out and take in the culture with the modern Athenians.

Split, Croatia

Split, Croatia

Beaches, historic sites and a melting pot of cultures can be found in this delightful city along the Adriatic Coast.

Tarragona, Spain

Tarragona, Spain

Cruise to the mysterious city of Tarragonna, where ancient ruins and a spicy nightlight are the main attractions.

Trieste, Italy

Trieste, Italy

Sit back and enjoy the sea breezes in Trieste, an Italian city that despite being close to Venice is more akin to Vienna, the capital of the Hapsburg Empire. 

Valencia, Spain

Valencia, Spain

Located on the Mediterranean Sea, Valencia is a city in Spain that attracts a lot of visitors to uncover the city’s past and revel in its modern achievements, most notably The City of Arts and Sciences.

Valletta, Malta

Valletta, Malta

This entire city is known as a UNESCO World Heritage Site leaving many historic areas and landmarks to explore during your visit to this impressive capital city.  

Venice, Italy

Experience the serene, romantic splendor of Venice, but don’t forget to check out its wonderful museums and neighborhoods located off the Grand Canal.

Photo Gallery for MSC Cruises Mediterranean Cruises

View our photo gallery of Mediterranean cruising photos from MSC Cruises. Remember, this is only a taste of the experiences waiting for you on a MSC Cruises Mediterranean cruise vacation.

Caserta Palace in Caserta, Italy

Caserta Palace in Caserta, Italy

Coastal City of Sorrento Italy

Coastal City of Sorrento Italy

Gondola ride on Venice Canal

Gondola ride on Venice Canal

Piazza del Plebiscito in Naples, Italy

Piazza del Plebiscito in Naples, Italy

Tripoli Ruins

Tripoli Ruins

African oasis in desert Sakkara MSC Cruises

African oasis in desert Sakkara

La Sagrada Família Barcelona Spain MSC Cruises

La Sagrada Família in Barcelona, Spain

Hasan Mosque II Casablanca, Morocco MSC Cruises

Hasan Mosque II in Casablanca, Morocco

Coast of Capri, Italy MSC Cruises Mediterranean

Coast of Capri, Italy

Parthenon in Athens, Greece MSC Cruises Europe

Parthenon in Athens, Greece

Dubrovnik, Croatia Coast MSC Cruises Mediterranean

Coast of Dubrovnik, Croatia

Caserta Palace in Caserta, Italy

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  1. Cruceros por el Mediterraneo 2019/2020

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